Adherence and compliance with mandatory vaccinations according to the national schedule and COVID-19 vaccination among healthcare workers

Abstract

This study analyzes adherence and compliance with mandatory vaccination schemes among healthcare workers, including the recommended COVID-19 vaccination schedule. The aim is to understand the behaviors and social drivers behind mandatory vaccination in a population considered highly exposed to infectious diseases and potential reservoirs for more vulnerable groups. The research was conducted with healthcare workers from the hospital sector in Ensenada, Buenos Aires Province, Argentina.

An observational, analytical, cross-sectional, and prospective study was carried out. A total of 269 healthcare workers were surveyed between October 2024 and February 2025 at the Hospital El Dique.

Although 67.3% of respondents reported being up to date with their vaccinations, none met the full vaccination requirements established by national regulations. The highest coverage rates were found for influenza (82.9%) and COVID-19 (79.2%) vaccines. A significant association was found between the presence of institutional vaccination campaigns and greater vaccine adherence (p = 0.002; OR = 3.0; 95% CI: 1.45–6.29).

The findings suggest that adherence increases when active institutional campaigns are in place, highlighting the importance of sustaining public vaccination policies with visible presence, adequate resources, and long-term continuity. This involves not only ensuring vaccine availability, but also investing in ongoing training, accessible communication strategies, and public engagement efforts to counter misinformation.